Journal of Geriatric Oncology
Volume 3, Issue 1 , Pages 17-23 , January 2012

Age, sex and gender impact multidimensional geriatric assessment in elderly cancer patients

  • C. Valentiny

      Affiliations

    • Department of Internal Medicine V (Hematology and Oncology), Innsbruck Medical University, Innsbruck, Austria
    • ,
  • G. Kemmler

      Affiliations

    • Department of Biological Psychiatry, Innsbruck Medical University, Innsbruck, Austria
    • ,
  • R. Stauder

      Affiliations

    • Department of Internal Medicine V (Hematology and Oncology), Innsbruck Medical University, Innsbruck, Austria
    • Corresponding Author InformationCorresponding author at: Department of Internal Medicine V (Haematology and Oncology), Innsbruck Medical University, Anichstrasse 35; 6020 Innsbruck, Austria. Tel.: +43 512 504 23255.

Received 30 May 2011 ,Revised 21 September 2011 ,Accepted 12 October 2011.

References 

  1. Carrreca I, Balducci L, Extermann M. Cancer in the older person. Cancer Treat Rev. 2005 Aug;31(5):380–402
  2. Lichtman SM, Balducci L, Aapro M. Geriatric oncology: a field coming of age. J Clin Oncol. May 10 2007;25(14):1821–1823
  3. Extermann M, Aapro M, Bernabei R, Cohen HJ, Droz JP, Lichtman S, et al. Task Force on CGA of the International Society of Geriatric Oncology. Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG). Crit Rev Oncol Hematol. 2005 Sep;55(3):241–252
  4. Balducci L. Aging, frailty, and chemotherapy. Cancer Control. Jan. 2007;14(1):7–12
  5. Stauder R, Foà R, Palumbo A, McVie JG. Challenges and perspectives in the individualised management of elderly blood cancer patients. Submitted for publication.
  6. Extermann M, Hurria A. Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol. 2007 May 10;25(14):1824–1831
  7. Stauder R, Moser K, Holzner B, Sperner-Unterweger B, Kemmler G. Six independent domains are defined by geriatric assessment in elderly cancer patients. Crit Rev Oncol Haematol. 2010;74:97–105
  8. Girre V, Falcou MC, Gisselbrecht M, Gridel G, Mosseri V, Bouleuc C, et al. Does a geriatric oncology consultation modify the cancer treatment plan for elderly patients?. J Gerontol A Biol Sci Med Sci. 2008 Jul;63(7):724–730
  9. Arber S, Cooper H. Gender differences in health in later life: the new paradox?. Soc Sci Med. 1999;48:61–76
  10. Denton M, Prus S, Walters V. Gender differences in health: a Canadian study of the psychosocial, structural and behavioural determinants of health. Soc Sci Med. 2004;58:2585–2600
  11. Murtagh KN, Hubert HB. Gender differences in physical disability among an elderly cohort. Am J Public Health. 2004;94(8):
  12. Miller AB, Hoogstraten B, Staquet M, Winkler A. Reposting results of cancer treatment. Cancer. 1981;47:207–214
  13. Karnofsky DA, Abelmann WH, Craver LF, Burchenal JH. The use of nitrogen mustards in the palliative treatment of cancer. Cancer. 1948;1:634–656
  14. Mahoney FI, Barthel DW. Functional evaluation: the Barthel index. Md State Med J. 1965;21:61–65
  15. Lawton MP, Brody EM. Instrumental activities of daily living scale (IADL). Gerontologist. 1969;9:179–186
  16. Cabrero- Garcia J, López-Pina JA. Aggregated measures of functional disability in a nationally representative sample of disabled people: analysis of dimensionality according to gender and severity of disability. Qual Life Res. 2008;17:425–436
  17. Podsiadlo Richardson S. The timed “Up & Go”: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. Feb. 1991;39(2):142–148
  18. Yesavage JA, Brink TL. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1983;17(1):37–49
  19. Folstein MF, Folstein SE, McHugh PR. Mini-mental state: a practical method for grading the state of patients for the clinician. J Psychiatr Res. 1975;12:189–198
  20. Miller MD, Towers A. A Manual of Guidelines for Scoring The Cumulative Illness Rating Scale for Geriatrics (CIRS)-G. May 1991;
  21. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: developing and validation. J Chron Dis. 1987;40(5):373–383
  22. Fydrich T, Geyer M, Hessel A, Sommer G, Brähler E. Fragebogen zur sozialen Unterstützung (F-SozU): Normierung an einer repräsentativen Stichprobe. Diagnostica. 1999;45:212–216
  23. Fydrich F, Sommer G, Brähler E. F-SozU, Fragebogen zur sozialen Unterstützung. Hogrefe Verlag GmbH& Co.KG; 2007;
  24. WHO . Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee. WHO Technical Report Series. 854. Geneva: World Health Organization; 1995;
  25. Alexandre Tda S, Cordeiro RC, Ramos LR. Factors associated to quality of life in active elderly. Rev Saude Publica. 2009;43(4):613–621
  26. Extermann M, Overcash J, Lyman GH, Parr J, Balducci L. Comorbidity and Functional Status are Independent in Older Cancer Patients. J Clin Oncol. 1998;16(4):1582–1587
  27. Repetto L, Venturino A, Vercelli M, Gianni W, Biancardi V, Casella C, et al. Performance status and comorbidity in elderly cancer patients compared with young patients with neoplasia and elderly patients without neoplastic conditions. Cancer. 1998;82(4):
  28. Jette AM, Branch LG. The Framingham disability study: II. Physical disability among the aging. Am J Public Health. 1981;71(11):
  29. Terret C, Zulian GB, Naiem A, Albrand G. Multidisciplinary approach to the geriatric oncology patient. J Clin Oncol. May 10 2007;25(14):1876–1881
  30. Dunlop DD, Hughes SL, Manheim LM. Disability in activities of daily living: patterns of change and a hierarchy of disability, D.D. Am J Public Health. 1997;87(3):
  31. Kiss A, Meryn S. Effect of sex and gender on psychosocial aspects of prostate and breast cancer. Br Med J. 2001;323:1056–1058
  32. Wedding U, Röhrig B, Klippstein A, Pientka L, Höffken K. Age, severe comorbidity and functional impairement independently contribute to poor survival in cancer patients. J Cancer Res Clin Oncol. 2007;133:945–950
  33. Garman KS, Cohen HJ. Functional status and elderly cancer patient. Crit Rev Oncol Hematol. 2002;43:191–208
  34. Leon- Munoz LM, López-García E, Graciani A, Guallar-Castillón P, Banegas JR, Rodríguez-Artalejo F. Functional status and use of health care services: longitudinal study on the older adult population in Spain. Maturitas. 2007;58:377–386
  35. Cacciatore F, Gallo C, Ferrara N, Abete P, Paolisso G, Canonico S, et al. Morbidity patterns in aged population in southern Italy. A survey sampling. Arch Gerontol Geriatr. 1998;26:201–213
  36. Kumar Pal S, Hurria A. Impact of age, sex, and comorbidity on cancer therapy and disease progression. J Clin Oncol. 2010 September 10;10(26):4086–4093
  37. Pinquart M, Höffken K, Silbereisen RK, Wedding U. Social support and survival in patients with acute myeloid leukaemia. Support Care Cancer. 2006;15:81–87Goal of work
  38. Hessel A, Geyer M, Plöttner G, Brähler E. Soziale Unterstützung im Alter- Normierung des Fragebogens zur Sozialen Unterstürtzung (F- SOZU) bei über 60jährigen. ZKPP Jg. 1998;46:245–266
  39. Dunkel D, Antretter E, Fröhlich-Walser S, Haring C. Evaluation of the short-form social support questionnaire (SOZU-K-22) in clinical and non-clinical samples. Psychother Psychosom Med Psychol. 2005 May;55(5):266–277
  40. Zunzunegui MV, Minicuci N, Blumstein T, Noale M, Deeg D, Jylhä M, et al. Gender differences in depressive symptoms among older adults: a cross- national comparison. Soc Psychiatry Psychiatr Epidemiol. 2007;42:198–207
  41. Kirchengast S, Haslinger B. Gender differences in health-related quality of life among healthy aged and old-aged Austrians: cross- sectional analysis. Gend Med. 2008;5(3):270–278

☆ Supported by Österreichische Krebshilfe-Krebsgesellschaft Tirol (RS), Qualitätsförderungsprogramm des Tiroler Gesundheitsfonds (RS) and Verein Senioren-Krebshilfe (RS).

PII: S1879-4068(11)00060-9

doi: 10.1016/j.jgo.2011.10.001

Journal of Geriatric Oncology
Volume 3, Issue 1 , Pages 17-23 , January 2012

Article Tools